Memphis - Take U.S. 61 south to Cleveland (about 110 miles). Once in Cleveland, turn right on to MS. Hwy 8 and proceed through the business district. Go through the 4th traffic signal (intersection of 8 and Fifth Avenue) and the main entrance to the campus is on the left.

Jackson - Take U.S. 49 north to Yazoo City.  In Yazoo City, follow Hwy 49 toward Greenwood.  Remain on 49 to Indianola (about 65-70 miles).  Turn left on U.S. 82 East (4-way stop). Proceed about ¾ mile MS Hwy 448. Turn right on to 448 and proceed 15 miles to Shaw.  Turn right on US Hwy 61 North into Cleveland.  (10.8 miles).  Turn Left onto Hwy 8 West.  Campus will be on the left. 

Vicksburg - Take U.S. 61 north into Cleveland (110 miles) to the intersection of Hwy 8 in Cleveland. Turn Left onto Hwy 8 West.  Campus will be on the left.  

For Interstate 55 Travelers from Jackson and Louisiana - Take I-55 north to Grenada and take Exit 206 (Miss. Hwys 7-8). Turn to left onto MS Hwy 8 West.  Hwy 8 bears right in Holcomb. Remain on Hwy 8 into Cleveland.  Campus will be on the left. 

For air travelers:
Memphis and Jackson airports, which are served by major carriers, are 2-2 ½ hours from Cleveland. The Mid-Delta Regional Airport at Greenville is served by Northwest Airlink flights from Memphis. The Greenville airport is 45 minutes from the campus.