Home » Academics » College of Arts and Sciences » Biological and Physical Sciences » Science Faculty and Staff » Chu, Arthur
Division of Biological and Physical Sciences
Dr. Arthur Chu
Associate Professor of Chemistry
|
B.S., Chung-Yuan University, Taiwan
Ph.D., University of Nevada, Reno
Courses taught by Dr. Chu
CHE 440/540. Biochemistry
Appointments Held
After graduation with Ph.D. in Biochemistry, Dr. Chu received post-doctoral training from Yale Pediatrics & Anesthesiology. He held many academic positions including Scientist II (Rice University), Chief Biochemist (Miami Heart Institute), and Assistant Director (Skin Bank, Detroit Receiving Hospital). Prior to joining DSU faculty, he was Associate Professor in Surgery at Wayne State University and taught Biochemistry in Juniata College, PA.
Scholarly Activity
- Editor for SlideWorld (biochemistry e-teaching)
- Inflammation & Allergy - Drug Targets (Editorial Board)
- Frontiers in Biosciences (Managing Editor)
- Expert Opinions on Biology Therapy (Reviewer)
- J. Haemostasis and Thrombosis (Reviewer)
- European J. Pharmacology (Reviewer)
- Archives of Biochemistry and Biophysics (Reviewer)
- J. Endotoxin Research (Reviewer)
- British J. Dermatology (Reviewer)
- Medical Research Institutes (U. K.): Diabetes & Thrombosis (Consultant)
- Medical Science Monitor (Member, Review Panel)
- Indian J. Surgery (Review Panel)
- Genesis Oncology Trust, New Zealand (Review board member)
Research Portfolios
Dr. Chu's research interests center on TF-initiated coagulation relevant to inflammation and thrombosis with special concerns in cardiovascular dysfunctions.
- Anticoagulation (review article in Current Vascular Pharmacology, 2004) [View as PDF]
- Blood coagulation axle (managing editor of a special issue of Frontiers in Bioscience on coagulation-inflammation-thrombosis) [View as PDF]
- Coagulation-inflammation-thrombosis circuit (review article in Cell Biochemistry & Function, 2005) [View as PDF]
- Role of hypercoagulability in inflammation (review article in Archives of Biochemistry & Biophysics, 2005 [View as PDF]; Chapter II in Handbook of Hematology Research, 2010) [View as PDF]
- Role of tissue factor in thrombosis (review article in Frontiers in Bioscience, 2006) [View as PDF]
Recent Publications
- Chu, A.J. (2010) Blood coagulation as an intrinsic pathway for proinflammation. Infl. Allergy Drug Targets 9, 32-44 [View as PDF]
- Chu, A.J. (2010) Chapter II: Blood Coagulation Fuels Inflammation Implementing a Blood Coagulation-Inflammation-Thrombosis Circuit. In: Handbook of Hematology Research (ed. by Tondre R. & Lebegue C.) Nova Science Publishers, Inc. p 33-86 [View as PDF]
- Chu, A. J. (2006) Role of tissue factor in thrombosis. Coagulation-Inflammation-Thrombosis circuit. Frontiers in Bioscience 11, 256-271. [View as PDF]
- Chu, A. J. (2005) Mini review: Tissue factor mediates inflammation. Archives of Biochemistry and Biophysics, 440, 123-132. [View as PDF]
- Chu, A. J., Chou, T-H., and Chen, B. DM. (2004) Prevention of colorectal cancer using COX-2 inhibitors: basic science and clinical applications. Frontiers in Bioscience 9, 2697-713.
- Chu, A.J. (2004) Tissue factor upregulation drives a thrombosis-inflammation circuit in relation to cardiovascular events. Cell Biochemistry & Function Dec. 22 [View as PDF]
- Chu, A.J. (2004) Biochemical strategies to anticoagulation: A comparative overview. Current Vascular Pharmacology 2, 199-228. [View as PDF]
- Chu, A.J., and Mathews, S. T. (2003) Anticoagulant potential of an antibody against factor VII. J. Surgical Research 114, 37-41.
- Chu, A. J., Mathews, S. T., Beydoun, S., and Houng, J. (2003) Novel anticoagulant polyethylenimine: Inhibition of thrombin-catalyzed fibrin formation. Archives Biochemistry Bophysics 415, 101-108.
- Chu, A. J. and Mathews, S. T. (2003) Poly-L-hisditine downregulates fibrinolysis. Blood Coaguation & Fibrinolysis 14, 27-32.
- Chu, A. J., Rauci, M., Nwobi, O.I., Mathews, S.T. and Beydoun, S. (2003) Novel anticoagulant activity of polyamino acid offsets bacterial endotoxin-induced extrinsic hypercoagulation: Downregulation of monocytic tissue factor-dependent FVII activation. J. Cardiovascular Pharmacology 42, 477-483.
- Chu, A. J., Lin, S-H., and Piasentin, E. (2002) Possible role of Marcks in the cellular modulation of monocytic tissue factor-initiated hypercoagulation. British Journal of Haematology 118, 569-576.
- Chu, A. J., Rauci, M., Nwobi, O.I., Mathews, S.T. and Beydoun, S. (2002) Novel anticoagulant activity of polybrene: Inhibition of monocytic tissue factor hypercoagulation following bacterial endotoxin induction. Blood Coagulation & Fibrinolysis 13, 123-128.
- Chu, A.J., Wang, Z.G., Raicu, M., Ramos, N. and Beydoun, S. (2001) Protamine inhibits tissue factor-initiated extrinsic coagulation. Br. J. Haematol. 115, 392-399.
- Chu, A.J.Wang, Z-G., Walton, M.A. and Seto, A. (2001) Involvement of MAPK activation in bacterial endotoxin-inducible tissue factor upregulation in human monocytic THP-1 cells. J. Surg. Res. 101, 85-90.
- Chu, A.J., Wang, Z.G., Nwobi, O. I. and Beydoun, S. (2001) Blockade by ruthenium red of tissue factor-initiated coagulation. Br. J. Pharmacol. 133, 659-664.
- Chu, A. J., Chen, B. M., Lin, H. and Beydoun, S. (2001) Antimicrobial peptide Buforin I inhibits tissue factor-initiated coagulation. Arch. Biochem. Biophys. 392, 3-7.
Delta State University > Arts and Sciences > DSU Sciences > Science Faculty > Dr. Chu